USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

USC-OGP 2-DE database  Search by                Maps             Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal World-2DPAGE Repository Exclude local DBs has only effect if a remote interface is selected

Searching in 'USC-OGP 2-DE database' for entry matching: MTX2_HUMAN USC-OGP 2-DE database:  MTX2_HUMAN MTX2_HUMAN General information about the entry View entry in simple text format Entry name MTX2_HUMAN Primary accession number O75431 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Metaxin-2; AltName: Full=Mitochondrial outer membrane import complex protein 2;. Gene name Name=MTX2 Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein UVEAL_MELANOMA_3-10 {UVEAL MELANOMA 3-10} Homo sapiens (Human)   map experimental info   UVEAL_MELANOMA_3-10 MAP LOCATIONS: SPOT OGP-1280: pI=5.93; Mw=26725 Cross-references UniProtKB/Swiss-Prot O75431; MTX2_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name MTX2_HUMAN Primary accession number O75431 Secondary accession number(s) A8JZZ4 Q53S50 Q53SQ2 Q5M7Z6 Q8IZ68 Sequence was last modified on  November 1, 1998 (version 1) Annotations were last modified on  March 15, 2017 (version 141) Name and origin of the protein Description RecName: Full=Metaxin-2; AltName: Full=Mitochondrial outer membrane import complex protein 2; Gene name Name=MTX2 Encoded on Name=MTX2 Keywords Acetylation; Alternative splicing; Complete proteome; Membrane; Mitochondrion; Mitochondrion outer membrane; Protein transport; Reference proteome; Transport. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL AF053551; AAC25105.1; -; mRNA EMBL AK289359; BAF82048.1; -; mRNA EMBL AK303564; BAG64587.1; -; mRNA EMBL AC016739; AAY14795.1; -; Genomic_DNA EMBL AC073069; AAX93188.1; -; Genomic_DNA EMBL CH471058; EAX11076.1; -; Genomic_DNA EMBL CH471058; EAX11078.1; -; Genomic_DNA EMBL BC017271; AAH17271.1; -; mRNA EMBL BC067831; AAH67831.1; -; mRNA EMBL BC088359; AAH88359.1; -; mRNA CCDS CCDS2272.1; -. [O75431-1]; . RefSeq NP_001006636.1; NM_001006635.2. [O75431-2]; . RefSeq NP_001306026.1; NM_001319097.1; . RefSeq NP_001306027.1; NM_001319098.1; . RefSeq NP_006545.1; NM_006554.4. [O75431-1]; . UniGene Hs.470728; -; . ProteinModelPortal O75431; -; . BioGrid 115894; 28; . IntAct O75431; 15; . MINT MINT-3001232; -; . STRING 9606.ENSP00000249442; -; . iPTMnet O75431; -; . PhosphoSitePlus O75431; -; . SwissPalm O75431; -; . BioMuta MTX2; -; . EPD O75431; -; . MaxQB O75431; -; . PaxDb O75431; -; . PeptideAtlas O75431; -; . PRIDE O75431; -; . TopDownProteomics O75431-1; -. [O75431-1]; . DNASU 10651; -; . Ensembl ENST00000249442; ENSP00000249442; ENSG00000128654. [O75431-1]; . GeneID 10651; -; . KEGG hsa:10651; -; . UCSC uc002ukx.4; human. [O75431-1]; . CTD 10651; -; . DisGeNET 10651; -; . GeneCards MTX2; -; . H-InvDB HIX0002618; -; . HGNC HGNC:7506; MTX2; . HPA HPA031550; -; . HPA HPA031551; -; . HPA HPA031552; -; . MIM 608555; gene; . neXtProt NX_O75431; -; . OpenTargets ENSG00000128654; -; . PharmGKB PA31308; -; . eggNOG KOG3027; Eukaryota; . eggNOG ENOG410XY7W; LUCA; . GeneTree ENSGT00530000063166; -; . HOGENOM HOG000231908; -; . HOVERGEN HBG003471; -; . InParanoid O75431; -; . KO K17776; -; . OMA PWPENAA; -; . OrthoDB EOG091G132X; -; . PhylomeDB O75431; -; . TreeFam TF313422; -; . Reactome R-HSA-1268020; Mitochondrial protein import; . ChiTaRS MTX2; human; . GenomeRNAi 10651; -; . PRO PR:O75431; -; . Proteomes UP000005640; Chromosome 2; . Bgee ENSG00000128654; -; . CleanEx HS_MTX2; -; . ExpressionAtlas O75431; baseline and differential; . Genevisible O75431; HS; . GO GO:0005741; C:mitochondrial outer membrane; TAS:ProtInc; . GO GO:0005739; C:mitochondrion; IDA:UniProtKB; . GO GO:0005730; C:nucleolus; IDA:HPA; . GO GO:0006839; P:mitochondrial transport; TAS:ProtInc; . GO GO:0006626; P:protein targeting to mitochondrion; IEA:InterPro; . Gene3D 1.20.1050.10; -; 1; . InterPro IPR010987; Glutathione-S-Trfase_C-like; . InterPro IPR033468; Metaxin_GST; . InterPro IPR019564; Sam37/metaxin_N; . Pfam PF17171; GST_C_6; 1; . Pfam PF10568; Tom37; 1; . SUPFAM SSF47616; SSF47616; 2; .

Gateways to other related servers

• The World-2DPAGE Constellation - Entry point to the world-wide 2-DPAGE resources.
• World-2DPAGE Repository - A public repository for gel-based proteomics data linked to protein identification published in the literature.
• World-2DPAGE Portal - A dynamic portal to query simultaneously world-wide gel-based proteomics databases.
• SWISS-2DPAGE - The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
• ExPASy - The resources web server of the Swiss Institute of Bioinformatics

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